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Peroxiredoxin1 Knockdown Inhibits Oral Carcinogenesis via Inducing Cell Senescence Dependent on Mitophagy

PURPOSE: Cellular senescence is a physiological phenomenon by which cells irreversibly lose their proliferative potential. It is not clear whether senescent cells are related to malignant transformation in oral precancerous lesions. The role of peroxiredoxin1 (Prx1)-induced cell senescence in OLK ma...

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Detalles Bibliográficos
Autores principales: Lu, Yunping, Li, Lingyu, Chen, Hui, Jing, Xinying, Wang, Min, Ge, Lihua, Yang, Jing, Zhang, Min, Tang, Xiaofei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812030/
https://www.ncbi.nlm.nih.gov/pubmed/33469304
http://dx.doi.org/10.2147/OTT.S284182