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Immune microenvironment features and efficacy of PD‐1/PD‐L1 blockade in non‐small cell lung cancer patients with EGFR or HER2 exon 20 insertions

BACKGROUND: Insertions in exon 20 (Ex20ins) of epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) are relatively insensitive to first‐ and second‐generation EGFR‐tyrosine kinase inhibitors (TKIs) in non‐small cell lung cancer (NSCLC). This study aimed to inve...

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Detalles Bibliográficos
Autores principales: Chen, Kaiyan, Pan, Guoqiang, Cheng, Guoping, Zhang, Fanrong, Xu, Yanjun, Huang, Zhiyu, Fan, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812071/
https://www.ncbi.nlm.nih.gov/pubmed/33210451
http://dx.doi.org/10.1111/1759-7714.13748