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RNF213 gene mutation in circulating tumor DNA detected by targeted next‐generation sequencing in the assisted discrimination of early‐stage lung cancer from pulmonary nodules

BACKGROUND: To distinguish early‐stage lung cancer from benign disease in pulmonary nodules, especially lesions with ground‐glass opacity (GGO), we assessed gene mutations of ctDNA in peripheral blood using targeted next‐generation sequencing (NGS). METHODS: Single pulmonary nodule patients without...

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Detalles Bibliográficos
Autores principales: Jiang, Ning, Zhou, Jie, Zhang, Wenhao, Li, Peichao, Liu, Yu, Shi, Hubo, Zhang, Chengke, Wang, Yunshan, Zhou, Chengjun, Peng, Chuanliang, Zhang, Weiquan, Hao, Yingtao, Sun, Qifeng, Li, Yuliang, Zhao, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812078/
https://www.ncbi.nlm.nih.gov/pubmed/33200540
http://dx.doi.org/10.1111/1759-7714.13741