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Therapy of lymphoma by immune checkpoint inhibitors: the role of T cells, NK cells and cytokine-induced tumor senescence

BACKGROUND: Although antibodies blocking immune checkpoints have already been approved for clinical cancer treatment, the mechanisms involved are not yet completely elucidated. Here we used a λ-MYC transgenic model of endogenously growing B-cell lymphoma to analyze the requirements for effective the...

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Detalles Bibliográficos
Autores principales: Ahmetlic, Fatima, Fauser, Josia, Riedel, Tanja, Bauer, Vera, Flessner, Carolin, Hömberg, Nadine, Hennel, Roman, Brenner, Ellen, Lauber, Kirsten, Röcken, Martin, Mocikat, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812096/
https://www.ncbi.nlm.nih.gov/pubmed/33441389
http://dx.doi.org/10.1136/jitc-2020-001660