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The landscape of kinase domain duplication in Chinese lung cancer patients

BACKGROUND: Kinase domain duplication (KDD) is a special type of large genomic rearrangement (LGR), occurring in the kinase domain of protein kinase genes. KDD of some lung cancer driver genes, such as EGFR: KDD, has been identified and implicated to be oncogenic in non-small cell lung cancer (NSCLC...

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Detalles Bibliográficos
Autores principales: Wu, Di, Xie, Yuancai, Jin, Chang’e, Qiu, Jinfan, Hou, Ting, Du, Haiwei, Chen, Songan, Xiang, Jianxing, Shi, Xi, Liu, Junling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812209/
https://www.ncbi.nlm.nih.gov/pubmed/33490154
http://dx.doi.org/10.21037/atm-20-7408