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The landscape of kinase domain duplication in Chinese lung cancer patients
BACKGROUND: Kinase domain duplication (KDD) is a special type of large genomic rearrangement (LGR), occurring in the kinase domain of protein kinase genes. KDD of some lung cancer driver genes, such as EGFR: KDD, has been identified and implicated to be oncogenic in non-small cell lung cancer (NSCLC...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812209/ https://www.ncbi.nlm.nih.gov/pubmed/33490154 http://dx.doi.org/10.21037/atm-20-7408 |