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Salvianolate ameliorates oxidative stress and podocyte injury through modulation of NOX4 activity in db/db mice

Podocyte injury is associated with albuminuria and the progression of diabetic nephropathy (DN). NADPH oxidase 4 (NOX4) is the main source of reactive oxygen species (ROS) in the kidney and NOX4 is up‐regulated in podocytes in response to high glucose. In the present study, the effects of Salvianola...

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Detalles Bibliográficos
Autores principales: Liang, Yiran, Liu, Hong, Fang, Yi, Lin, Pan, Lu, Zhihui, Zhang, Pan, Jiao, Xiaoyan, Teng, Jie, Ding, Xiaoqiang, Dai, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812253/
https://www.ncbi.nlm.nih.gov/pubmed/33332718
http://dx.doi.org/10.1111/jcmm.16165