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Hepatic stellate cells specific liposomes with the Toll‐like receptor 4 shRNA attenuates liver fibrosis

The hepatic stellate cells (HSCs) play a significant role in the onset of liver fibrosis, which can be treated by the inhibition and reversal of HSC activation. The RNA interference‐mediated TLR4 gene silencing might be a potential therapeutic approach for liver fibrosis. The crucial challenge in th...

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Detalles Bibliográficos
Autores principales: Zhang, Yuwei, Li, Yang, Mu, Tong, Tong, Nanwei, Cheng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812270/
https://www.ncbi.nlm.nih.gov/pubmed/33336563
http://dx.doi.org/10.1111/jcmm.16209