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Licochalcone A inhibits EGFR signalling and translationally suppresses survivin expression in human cancer cells

Dysfunction of epidermal growth factor receptor (EGFR) signalling plays a critical role in the oncogenesis of non–small‐cell lung cancer (NSCLC). Here, we reported the natural product, licochalcone A, exhibited a profound anti‐tumour efficacy through directly targeting EGFR signalling. Licochalcone...

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Detalles Bibliográficos
Autores principales: Gao, Feng, Li, Ming, Yu, Xinfang, Liu, Wenbin, Zhou, Li, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812290/
https://www.ncbi.nlm.nih.gov/pubmed/33247550
http://dx.doi.org/10.1111/jcmm.16135