Ubiquitously specific protease 4 inhibitor‐Vialinin A attenuates inflammation and fibrosis in S100‐induced hepatitis mice through Rheb/mTOR signalling

Inflammation and fibrosis are major consequences of autoimmune hepatitis, however, the therapeutic mechanism remains to be investigated. USP4 is a deubiquitinating enzyme and plays an important role in tissue fibrosis and immune disease. Vialinin A is an extract from mushroom and is a specific USP4...

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Detalles Bibliográficos
Autores principales: Xu, Jie, Chen, Dazhi, Jin, Lanling, Chen, Zhengkang, Tu, Yulu, Huang, Xiaozhe, Xue, Feiben, Xu, Jialu, Chen, Mingzhuan, Wang, Xiaodong, Chen, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812299/
https://www.ncbi.nlm.nih.gov/pubmed/33295107
http://dx.doi.org/10.1111/jcmm.16180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812299/
https://www.ncbi.nlm.nih.gov/pubmed/33295107
http://dx.doi.org/10.1111/jcmm.16180

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