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Linagliptin prevents left ventricular stiffening by reducing titin cleavage and hypophosphorylation

The metabolic syndrome (MetS) is an escalating problem worldwide, causing left ventricular stiffening, an early characteristic of diastolic dysfunction for which no treatment exists. As diastolic dysfunction and stiffening in MetS patients are associated with increased circulating dipeptidyl peptida...

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Detalles Bibliográficos
Autores principales: Cuijpers, Ilona, Papageorgiou, Anna‐Pia, Carai, Paolo, Herwig, Melissa, Mügge, Andreas, Klein, Thomas, Hamdani, Nazha, Jones, Elizabeth A. V., Heymans, Stephane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812306/
https://www.ncbi.nlm.nih.gov/pubmed/33295687
http://dx.doi.org/10.1111/jcmm.16122