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Combination Therapy Using Prothrombin Complex Concentrate and Vitamin K in Anticoagulated Patients with Traumatic Intracranial Hemorrhage Prevents Progressive Hemorrhagic Injury: A Historically Controlled Study

Warfarin remains crucially involved in the treatment of patients at thrombotic or thromboembolic risk. However, warfarin increases the mortality rate among patients with traumatic intracranial hemorrhage (TICH) through progressive hemorrhagic injury (PHI). Therefore, a rapid anticoagulation reversal...

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Detalles Bibliográficos
Autores principales: KOYAMA, Hiroshi, YAGI, Kenji, HARA, Keijiro, MATSUBARA, Shunji, TAO, Yoshifumi, UNO, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Neurosurgical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812312/
https://www.ncbi.nlm.nih.gov/pubmed/33208582
http://dx.doi.org/10.2176/nmc.oa.2020-0252