Exosomes derived from osteogenic tumor activate osteoclast differentiation and concurrently inhibit osteogenesis by transferring COL1A1‐targeting miRNA‐92a‐1‐5p

In patients with prostate cancer (PCa), bone lesions appear osteoblastic in radiographs; however, pathological fractures frequently occur in PCa patients, and bone resorption is observed in all metastatic lesions under histopathologic assessment. The mechanisms that balance the activities of osteobl...

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Detalles Bibliográficos
Autores principales: Yu, Lijuan, Sui, Bingdong, Fan, Weixiao, Lei, Lin, Zhou, Lei, Yang, Liu, Diao, Yanjun, Zhang, Yue, Li, Zhuo, Liu, Jiayun, Hao, Xiaoke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812369/
https://www.ncbi.nlm.nih.gov/pubmed/33489015
http://dx.doi.org/10.1002/jev2.12056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812369/
https://www.ncbi.nlm.nih.gov/pubmed/33489015
http://dx.doi.org/10.1002/jev2.12056

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