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Exosomes derived from osteogenic tumor activate osteoclast differentiation and concurrently inhibit osteogenesis by transferring COL1A1‐targeting miRNA‐92a‐1‐5p
In patients with prostate cancer (PCa), bone lesions appear osteoblastic in radiographs; however, pathological fractures frequently occur in PCa patients, and bone resorption is observed in all metastatic lesions under histopathologic assessment. The mechanisms that balance the activities of osteobl...
Autores principales: | Yu, Lijuan, Sui, Bingdong, Fan, Weixiao, Lei, Lin, Zhou, Lei, Yang, Liu, Diao, Yanjun, Zhang, Yue, Li, Zhuo, Liu, Jiayun, Hao, Xiaoke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812369/ https://www.ncbi.nlm.nih.gov/pubmed/33489015 http://dx.doi.org/10.1002/jev2.12056 |
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