Conserved missense variant in ALDH1A3 ortholog impairs fecundity in C. elegans

Accumulating evidence demonstrates that mutations in ALDH1A3 (the aldehyde dehydrogenase 1 family, member A3) are associated with developmental defects. The ALDH1A3 enzyme catalyzes retinoic acid biosynthesis and is essential to patterning and neuronal differentiation in the development of embryonic...

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Detalles Bibliográficos
Autores principales: Wong, Wan-Rong, Maher, Shayda, Oh, Jun Young, Brugman, Katherine I, Gharib, Shahla, Sternberg, Paul W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2021
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812383/
https://www.ncbi.nlm.nih.gov/pubmed/33474529
http://dx.doi.org/10.17912/micropub.biology.000357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812383/
https://www.ncbi.nlm.nih.gov/pubmed/33474529
http://dx.doi.org/10.17912/micropub.biology.000357

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