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Conserved missense variant in ALDH1A3 ortholog impairs fecundity in C. elegans
Accumulating evidence demonstrates that mutations in ALDH1A3 (the aldehyde dehydrogenase 1 family, member A3) are associated with developmental defects. The ALDH1A3 enzyme catalyzes retinoic acid biosynthesis and is essential to patterning and neuronal differentiation in the development of embryonic...
Autores principales: | Wong, Wan-Rong, Maher, Shayda, Oh, Jun Young, Brugman, Katherine I, Gharib, Shahla, Sternberg, Paul W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Caltech Library
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812383/ https://www.ncbi.nlm.nih.gov/pubmed/33474529 http://dx.doi.org/10.17912/micropub.biology.000357 |
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