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Maladaptive Changes Associated With Cardiac Aging Are Sex-Specific and Graded by Frailty and Inflammation in C57BL/6 Mice

We investigated whether late-life changes in cardiac structure and function were related to high levels of frailty and inflammation in male and female mice. Frailty (frailty index), ventricular structure/function (echocardiography), and serum cytokines (multiplex immunoassay) were measured in 16- an...

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Detalles Bibliográficos
Autores principales: Kane, Alice E, Bisset, Elise S, Heinze-Milne, Stefan, Keller, Kaitlyn M, Grandy, Scott A, Howlett, Susan E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812442/
https://www.ncbi.nlm.nih.gov/pubmed/32857156
http://dx.doi.org/10.1093/gerona/glaa212