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Maladaptive Changes Associated With Cardiac Aging Are Sex-Specific and Graded by Frailty and Inflammation in C57BL/6 Mice
We investigated whether late-life changes in cardiac structure and function were related to high levels of frailty and inflammation in male and female mice. Frailty (frailty index), ventricular structure/function (echocardiography), and serum cytokines (multiplex immunoassay) were measured in 16- an...
Autores principales: | Kane, Alice E, Bisset, Elise S, Heinze-Milne, Stefan, Keller, Kaitlyn M, Grandy, Scott A, Howlett, Susan E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812442/ https://www.ncbi.nlm.nih.gov/pubmed/32857156 http://dx.doi.org/10.1093/gerona/glaa212 |
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