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Age of natural menopause onset in BRCA1/2 carriers – systematic review and meta-analysis

INTRODUCTION: Germinal pathogenic variants in BRCA1 and BRCA2 genes are associated with high risk of cancers, including breast, ovary, fallopian tubes and primary peritoneal. Non-oncological implications of germline pathogenic variants in BRCA1 and BRCA2 genes, complicating reproductive health are l...

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Detalles Bibliográficos
Autores principales: Kępczyński, Łukasz, Połatyńska, Katarzyna, Nykel, Anna, Sałamunia, Jordan, Kałużewski, Tadeusz, Kużawczyk, Andrzej, Gach, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812531/
https://www.ncbi.nlm.nih.gov/pubmed/33488327
http://dx.doi.org/10.5114/pm.2020.101946