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Fucoidan Inhibits NLRP3 Inflammasome Activation by Enhancing p62/SQSTM1-Dependent Selective Autophagy to Alleviate Atherosclerosis

NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome activation contributes to the progression of atherosclerosis, and autophagy inhibits inflammasome activation by targeting macrophages. We investigated whether fucoidan, a marine sulfated polysaccharide derived from brown seaweed...

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Detalles Bibliográficos
Autores principales: Cheng, Yufei, Pan, Xudong, Wang, Jing, Li, Xu, Yang, Shaonan, Yin, Ruihua, Ma, Aijun, Zhu, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812546/
https://www.ncbi.nlm.nih.gov/pubmed/33505579
http://dx.doi.org/10.1155/2020/3186306