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Generation of HIV-resistant cells with a single-domain antibody: implications for HIV-1 gene therapy

The cure or functional cure of the “Berlin patient” and “London patient” indicates that infusion of HIV-resistant cells could be a viable treatment strategy. Very recently, we genetically linked a short-peptide fusion inhibitor with a glycosylphosphatidylinositol (GPI) attachment signal, rendering m...

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Detalles Bibliográficos
Autores principales: Jin, Hongliang, Tang, Xiaoran, Li, Li, Chen, Yue, Zhu, Yuanmei, Chong, Huihui, He, Yuxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812570/
https://www.ncbi.nlm.nih.gov/pubmed/33462383
http://dx.doi.org/10.1038/s41423-020-00627-y