Suppression of Allograft Fibrosis by Regulation of Mammalian Target of Rapamycin-Related Protein Expression in Kidney-Transplanted Recipients Treated with Everolimus and Reduced Tacrolimus

BACKGROUND: Although renoprotective effects of everolimus (EVR) in kidney transplantation (KTx) have been widely reported, its pathophysiological mechanism remains unclear. MATERIAL/METHODS: We compared changes in eGFR (ΔGFR, ml/min/1.73 m(2)) and the ratio of the fibrotic area in biopsy specimens (...

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Detalles Bibliográficos
Autores principales: Nishioka, Shun, Ishimura, Takeshi, Endo, Takahito, Yokoyama, Naoki, Ogawa, Satoshi, Fujisawa, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812696/
https://www.ncbi.nlm.nih.gov/pubmed/33431785
http://dx.doi.org/10.12659/AOT.926476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812696/
https://www.ncbi.nlm.nih.gov/pubmed/33431785
http://dx.doi.org/10.12659/AOT.926476

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