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Cross-subunit interactions that stabilize open states mediate gating in NMDA receptors

NMDA receptors are excitatory channels with critical functions in the physiology of central synapses. Their activation reaction proceeds as a series of kinetically distinguishable, reversible steps, whose structural bases are currently under investigation. Very likely, the earliest steps include glu...

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Detalles Bibliográficos
Autores principales: Iacobucci, Gary J., Wen, Han, Helou, Matthew, Liu, Beiying, Zheng, Wenjun, Popescu, Gabriela K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812756/
https://www.ncbi.nlm.nih.gov/pubmed/33384330
http://dx.doi.org/10.1073/pnas.2007511118