Induction of spontaneous human neocentromere formation and long-term maturation

Human centromeres form primarily on α-satellite DNA but sporadically arise de novo at naive ectopic loci, creating neocentromeres. Centromere inheritance is driven primarily by chromatin containing the histone H3 variant CENP-A. Here, we report a chromosome engineering system for neocentromere forma...

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Detalles Bibliográficos
Autores principales: Murillo-Pineda, Marina, Valente, Luis P., Dumont, Marie, Mata, João F., Fachinetti, Daniele, Jansen, Lars E.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812830/
https://www.ncbi.nlm.nih.gov/pubmed/33443568
http://dx.doi.org/10.1083/jcb.202007210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812830/
https://www.ncbi.nlm.nih.gov/pubmed/33443568
http://dx.doi.org/10.1083/jcb.202007210

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