Cargando…

Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly

The pericentriolar material (PCM) that accumulates around the centriole expands during mitosis and nucleates microtubules. Here, we show the cooperative roles of the centriole and PCM scaffold proteins, pericentrin and CDK5RAP2, in the recruitment of CEP192 to spindle poles during mitosis. Systemati...

Descripción completa

Detalles Bibliográficos
Autores principales: Chinen, Takumi, Yamazaki, Kaho, Hashimoto, Kaho, Fujii, Ken, Watanabe, Koki, Takeda, Yutaka, Yamamoto, Shohei, Nozaki, Yuka, Tsuchiya, Yuki, Takao, Daisuke, Kitagawa, Daiju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812875/
https://www.ncbi.nlm.nih.gov/pubmed/33443571
http://dx.doi.org/10.1083/jcb.202006085