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Competition-Based Cell Assay Employing Soluble T Cell Receptors to Assess MHC Class II Antigen Processing and Presentation

Accurate assessment of antigen-specific immune responses is critical in the development of safe and efficacious biotherapeutics and vaccines. Endosomal processing of a protein antigen followed by presentation on major histocompatibility complex (MHC) class II constitute necessary steps in the induct...

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Detalles Bibliográficos
Autores principales: Tasker, Carley, Patel, Jenny, Jawa, Vibha, Maamary, Jad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812987/
https://www.ncbi.nlm.nih.gov/pubmed/33459871
http://dx.doi.org/10.1208/s12248-020-00553-x