Cargando…

Competition-Based Cell Assay Employing Soluble T Cell Receptors to Assess MHC Class II Antigen Processing and Presentation

Accurate assessment of antigen-specific immune responses is critical in the development of safe and efficacious biotherapeutics and vaccines. Endosomal processing of a protein antigen followed by presentation on major histocompatibility complex (MHC) class II constitute necessary steps in the induct...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tasker, Carley, Patel, Jenny, Jawa, Vibha, Maamary, Jad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812987/ https://www.ncbi.nlm.nih.gov/pubmed/33459871 http://dx.doi.org/10.1208/s12248-020-00553-x

Ejemplares similares

Use of soluble MHC class II/peptide multimers to detect antigen-specific T cells in human disease
por: Bill, Jerome R, et al.
Publicado: (2002)

MHC Class II Auto-Antigen Presentation is Unconventional
por: Sadegh-Nasseri, Scheherazade, et al.
Publicado: (2015)

Proteolysis and antigen presentation by MHC class II molecules
por: Bryant, Paula Wolf, et al.
Publicado: (2002)

Induction of tolerance against the arthritogenic antigen with type-II collagen peptide-linked soluble MHC class II molecules
por: Park, Yoon-Kyung, et al.
Publicado: (2016)

Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation
por: Wieczorek, Marek, et al.
Publicado: (2017)

Direct Activation of Human Dendritic Cells by Particle-Bound but Not Soluble MHC Class II Ligand
por: Baleeiro, Renato B., et al.
Publicado: (2013)

Expression of MHC Class II Antigens During Xenopus Development
por: Du Pasquier, Louis, et al.
Publicado: (1990)

Antigen Processing for MHC Class II Presentation via Autophagy
por: Münz, Christian
Publicado: (2012)

Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells
por: Kleijmeer, Monique, et al.
Publicado: (2001)

Visualizing Antigen Specific CD4+ T Cells using MHC Class II Tetramers
por: James, Eddie A., et al.
Publicado: (2009)

Macropinocytosis in phagocytes: regulation of MHC class-II-restricted antigen presentation in dendritic cells
por: Liu, Zhenzhen, et al.
Publicado: (2015)

Presentation of Exogenous Antigens on Major Histocompatibility Complex (MHC) Class I and MHC Class II Molecules Is Differentially Regulated during Dendritic Cell Maturation
por: Delamarre, Lélia, et al.
Publicado: (2003)

CD8(+) T-cell cross-competition is governed by peptide–MHC class I stability
por: Galea, Ian, et al.
Publicado: (2012)

MHC class II–restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell–mediated autoimmunity
por: Irla, Magali, et al.
Publicado: (2010)

MHC Class II and Non-MHC Class II Genes Differentially Influence Humoral Immunity to Bacillus anthracis Lethal Factor and Protective Antigen
por: Garman, Lori, et al.
Publicado: (2012)

Class II MHC Self-Antigen Presentation in Human B and T Lymphocytes
por: Costantino, Cristina Maria, et al.
Publicado: (2012)

HLA-DO and Its Role in MHC Class II Antigen Presentation
por: Poluektov, Yuri O., et al.
Publicado: (2013)

Targeting the MHC Class II antigen presentation pathway in cancer immunotherapy
por: Thibodeau, Jacques, et al.
Publicado: (2012)

Angiotensin converting enzyme affects the presentation of MHC class II antigens
por: Zhao, Tuantuan, et al.
Publicado: (2017)

Influence of DM-sensitivity on immunogenicity of MHC class II restricted antigens
por: Bernhardt, Anna Luise, et al.
Publicado: (2021)

Expression of MHC class II antigens in human B-cell leukaemia and non-Hodgkin's lymphoma.
por: Guy, K., et al.
Publicado: (1986)

Early BCR Events and Antigen Capture, Processing, and Loading on MHC Class II on B Cells
por: Avalos, Ana M., et al.
Publicado: (2014)

Corneal Epithelial Cells Exhibit Myeloid Characteristics and Present Antigen via MHC Class II
por: Royer, Derek J., et al.
Publicado: (2018)

Cross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell Subsets
por: Gutiérrez-Martínez, Enric, et al.
Publicado: (2015)

Schistosoma japonicum Soluble Egg Antigens Attenuate IFN-γ-Induced MHC Class II Expression in RAW 264.7 Macrophages
por: Tang, Gui-Xia, et al.
Publicado: (2012)

Characterization of Antigenic MHC-Class-I-Restricted T Cell Epitopes in the Glycoprotein of Ebolavirus
por: Powlson, Jonathan, et al.
Publicado: (2019)

Involvement of autophagy in MHC class I antigen presentation
por: Øynebråten, Inger
Publicado: (2020)

Mechanistic diversity in MHC class I antigen recognition
por: Barbosa, Camila R. R., et al.
Publicado: (2021)

MHC Class II Polymorphisms, Autoreactive T-Cells, and Autoimmunity
por: Tsai, Sue, et al.
Publicado: (2013)

Hematopoietic Cell Transplantation for MHC Class II Deficiency
por: Lum, Su Han, et al.
Publicado: (2019)

Lymph node stromal cells constrain immunity via MHC class II self-antigen presentation
por: Baptista, Antonio P, et al.
Publicado: (2014)

MHC class II expression and potential antigen-presenting cells in the retina during experimental autoimmune uveitis
por: Lipski, Deborah A., et al.
Publicado: (2017)

Structural Properties of MHC Class II Ligands, Implications for the Prediction of MHC Class II Epitopes
por: Jørgensen, Kasper Winther, et al.
Publicado: (2010)

Antigen presentation by liposomes bearing class II MHC and membrane IL-1.
por: Bakouche, O., et al.
Publicado: (1990)

Toward a Network Model of MHC Class II-Restricted Antigen Processing
por: Miller, Michael A., et al.
Publicado: (2013)

HLA-DO as the Optimizer of Epitope Selection for MHC Class II Antigen Presentation
por: Poluektov, Yuri O., et al.
Publicado: (2013)

Footprints of antigen processing boost MHC class II natural ligand predictions
por: Barra, Carolina, et al.
Publicado: (2018)

Causal ALS genes impact the MHC class II antigen presentation pathway
por: Chi, Binkai, et al.
Publicado: (2023)

Thymus dictates major histocompatibility complex (MHC) specificity and immune response gene phenotype of class II MHC-restricted T cells but not of class I MHC-restricted T cells
Publicado: (1984)

Increased yields and biological potency of knob-into-hole-based soluble MHC class II molecules
por: Serra, Pau, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_cpuvk9mfl7c367rat3o4p7tnnq