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Steroidal and non-steroidal mineralocorticoid receptor antagonists in cardiorenal medicine
This review covers the last 80 years of remarkable progress in the development of mineralocorticoid receptor (MR) antagonists (MRAs) from synthesis of the first mineralocorticoid to trials of nonsteroidal MRAs. The MR is a nuclear receptor expressed in many tissues/cell types including the kidney, h...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813624/ https://www.ncbi.nlm.nih.gov/pubmed/33099609 http://dx.doi.org/10.1093/eurheartj/ehaa736 |