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The Anti-apoptotic Role of 3′-Untranslational Region in Response to Angiotensin II via Mcl1 Expression

Myeloid cell leukemia 1 (Mcl1), an abundant protein in the myocardium, plays an essential role in fibrosis and anti-inflammation in cardiomyocytes to prevent heart failure. However, whether Mcl1 3′-untranslated regions (3′-UTR) has the cardio-protecting function remains unclear. Down-regulation of M...

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Detalles Bibliográficos
Autores principales: Lyu, Dayin, Yan, Hong, Chen, Liyang, Zhang, Lingmin, Du, Yanfeng, Ding, Lexi, Lu, Qiulun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813760/
https://www.ncbi.nlm.nih.gov/pubmed/33469534
http://dx.doi.org/10.3389/fcell.2020.593955