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The Blockade of TACE-Dependent EGF Receptor Activation by Losartan-Erlotinib Combination Attenuates Renal Fibrosis Formation in 5/6-Nephrectomized Rats Under Vitamin D Deficiency
Chronic kidney disease (CKD) has been considered a major public health issue. In addition to cardiovascular diseases and infections, hypovitaminosis D has been considered a non-traditional aggravating factor for CKD progression. Interstitial fibrosis is a hallmark of CKD strongly correlated with det...
Autores principales: | Gonçalves, Janaína Garcia, Canale, Daniele, de Bragança, Ana Carolina, Seguro, Antonio Carlos, Shimizu, Maria Heloisa Massola, Volpini, Rildo Aparecido |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813781/ https://www.ncbi.nlm.nih.gov/pubmed/33469545 http://dx.doi.org/10.3389/fmed.2020.609158 |
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