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Regulation of Decay Accelerating Factor Primes Human Germinal Center B Cells for Phagocytosis

Germinal centers (GC) are sites for extensive B cell proliferation and homeostasis is maintained by programmed cell death. The complement regulatory protein Decay Accelerating Factor (DAF) blocks complement deposition on host cells and therefore also phagocytosis of cells. Here, we show that B cells...

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Detalles Bibliográficos
Autores principales: Dernstedt, Andy, Leidig, Jana, Holm, Anna, Kerkman, Priscilla F., Mjösberg, Jenny, Ahlm, Clas, Henriksson, Johan, Hultdin, Magnus, Forsell, Mattias N. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813799/
https://www.ncbi.nlm.nih.gov/pubmed/33469456
http://dx.doi.org/10.3389/fimmu.2020.599647