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Regulation of Decay Accelerating Factor Primes Human Germinal Center B Cells for Phagocytosis
Germinal centers (GC) are sites for extensive B cell proliferation and homeostasis is maintained by programmed cell death. The complement regulatory protein Decay Accelerating Factor (DAF) blocks complement deposition on host cells and therefore also phagocytosis of cells. Here, we show that B cells...
Autores principales: | Dernstedt, Andy, Leidig, Jana, Holm, Anna, Kerkman, Priscilla F., Mjösberg, Jenny, Ahlm, Clas, Henriksson, Johan, Hultdin, Magnus, Forsell, Mattias N. E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813799/ https://www.ncbi.nlm.nih.gov/pubmed/33469456 http://dx.doi.org/10.3389/fimmu.2020.599647 |
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