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miR-541-3p enhances the radiosensitivity of prostate cancer cells by inhibiting HSP27 expression and downregulating β-catenin

Heat shock protein 27 (HSP27), a regulator of cell survival, can enhance the resistance of cancer cells to radiotherapy. As microRNA-541-3p (miR-541-3p) was recently predicted to be a putative upstream modulator of HSP27, the present study was designed to investigate the function and mechanism under...

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Detalles Bibliográficos
Autores principales: He, Zhenhua, Shen, Fuhui, Qi, Ping, Zhai, Zhenxing, Wang, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813831/
https://www.ncbi.nlm.nih.gov/pubmed/33462201
http://dx.doi.org/10.1038/s41420-020-00387-8