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DNA methylome signatures of prenatal exposure to synthetic glucocorticoids in hippocampus and peripheral whole blood of female guinea pigs in early life

Synthetic glucocorticoids (sGC) are administered to women at risk of preterm delivery, approximately 10% of all pregnancies. In animal models, offspring exposed to elevated glucocorticoids, either by administration of sGC or endogenous glucocorticoids as a result of maternal stress, show increased r...

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Detalles Bibliográficos
Autores principales: Sasaki, Aya, Eng, Margaret E., Lee, Abigail H., Kostaki, Alisa, Matthews, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813870/
https://www.ncbi.nlm.nih.gov/pubmed/33462183
http://dx.doi.org/10.1038/s41398-020-01186-6