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DNA methylome signatures of prenatal exposure to synthetic glucocorticoids in hippocampus and peripheral whole blood of female guinea pigs in early life
Synthetic glucocorticoids (sGC) are administered to women at risk of preterm delivery, approximately 10% of all pregnancies. In animal models, offspring exposed to elevated glucocorticoids, either by administration of sGC or endogenous glucocorticoids as a result of maternal stress, show increased r...
Autores principales: | Sasaki, Aya, Eng, Margaret E., Lee, Abigail H., Kostaki, Alisa, Matthews, Stephen G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813870/ https://www.ncbi.nlm.nih.gov/pubmed/33462183 http://dx.doi.org/10.1038/s41398-020-01186-6 |
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