Arsenic trioxide induces macrophage autophagy and atheroprotection by regulating ROS-dependent TFEB nuclear translocation and AKT/mTOR pathway

Inducing autophagy and inhibiting apoptosis may provide a therapeutic treatment for atherosclerosis (AS). For the treatment of progressive AS, arsenic trioxide (ATO) has been used to coat vascular stents. However, the effect of ATO on autophagy of macrophages is still unknown. Therefore, the aims of...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, Shaohong, Wan, Xin, Zou, Xiaoyi, Sun, Song, Hao, Xinran, Liang, Chenchen, Zhang, Zhenming, Zhang, Fangni, Sun, Bo, Li, Hulun, Yu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814005/
https://www.ncbi.nlm.nih.gov/pubmed/33462182
http://dx.doi.org/10.1038/s41419-020-03357-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814005/
https://www.ncbi.nlm.nih.gov/pubmed/33462182
http://dx.doi.org/10.1038/s41419-020-03357-1

Ejemplares similares