Cargando…

Wnt5a promotes renal tubular inflammation in diabetic nephropathy by binding to CD146 through noncanonical Wnt signaling

Immune and inflammatory factors have emerged as key pathophysiological mechanisms in the progression of diabetic renal injury. Noncanonical Wnt5a signaling plays an essential role in obesity- or diabetes-induced metabolic dysfunction and inflammation, but its explicit molecular mechanisms and biolog...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xiaomei, Wen, Jiejun, Dong, Yang, Zhang, Qunzi, Guan, Jian, Liu, Feng, Zhou, Ting, Li, Ze, Fan, Ying, Wang, Niansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814016/
https://www.ncbi.nlm.nih.gov/pubmed/33462195
http://dx.doi.org/10.1038/s41419-020-03377-x