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Oxidative stress activates NORAD expression by H3K27ac and promotes oxaliplatin resistance in gastric cancer by enhancing autophagy flux via targeting the miR-433-3p

Oxaliplatin resistance undermines its curative effects on cancer and usually leads to local recurrence. The oxidative stress induced DNA damage repair response is an important mechanism for inducing oxaliplatin resistance by activating autophagy. ELISA is used to detect target genes expression. TMT-...

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Detalles Bibliográficos
Autores principales: Wang, Jizhao, Sun, Yuchen, Zhang, Xing, Cai, Hui, Zhang, Cheng, Qu, Hangying, Liu, Lin, Zhang, Mingxin, Fu, Junke, Zhang, Jia, Wang, Jiansheng, Zhang, Guangjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814071/
https://www.ncbi.nlm.nih.gov/pubmed/33462197
http://dx.doi.org/10.1038/s41419-020-03368-y