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Synaptic processes and immune-related pathways implicated in Tourette syndrome

Tourette syndrome (TS) is a neuropsychiatric disorder of complex genetic architecture involving multiple interacting genes. Here, we sought to elucidate the pathways that underlie the neurobiology of the disorder through genome-wide analysis. We analyzed genome-wide genotypic data of 3581 individual...

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Detalles Bibliográficos
Autores principales: Tsetsos, Fotis, Yu, Dongmei, Sul, Jae Hoon, Huang, Alden Y., Illmann, Cornelia, Osiecki, Lisa, Darrow, Sabrina M., Hirschtritt, Matthew E., Greenberg, Erica, Muller-Vahl, Kirsten R., Stuhrmann, Manfred, Dion, Yves, Rouleau, Guy A., Aschauer, Harald, Stamenkovic, Mara, Schlögelhofer, Monika, Sandor, Paul, Barr, Cathy L., Grados, Marco A., Singer, Harvey S., Nöthen, Markus M., Hebebrand, Johannes, Hinney, Anke, King, Robert A., Fernandez, Thomas V., Barta, Csaba, Tarnok, Zsanett, Nagy, Peter, Depienne, Christel, Worbe, Yulia, Hartmann, Andreas, Budman, Cathy L., Rizzo, Renata, Lyon, Gholson J., McMahon, William M., Batterson, James R., Cath, Danielle C., Malaty, Irene A., Okun, Michael S., Berlin, Cheston, Woods, Douglas W., Lee, Paul C., Jankovic, Joseph, Robertson, Mary M., Gilbert, Donald L., Brown, Lawrence W., Coffey, Barbara J., Dietrich, Andrea, Hoekstra, Pieter J., Kuperman, Samuel, Zinner, Samuel H., Wagner, Michael, Knowles, James A., Jeremy Willsey, A., Tischfield, Jay A., Heiman, Gary A., Cox, Nancy J., Freimer, Nelson B., Neale, Benjamin M., Davis, Lea K., Coppola, Giovanni, Mathews, Carol A., Scharf, Jeremiah M., Paschou, Peristera, Darrow, Sabrina, Kurlan, Roger, Leckman, James F., Smit, Jan H., Aschauer, Harald Aschauer Harald, Konstantinidis, Anastasios, Müller-Vahl, Kirsten, Wolanczyk, Tomasz, Brown, Lawrence, Cheon, Keun-Ah, Garcia-Delgar, Blanca, Gilbert, Donald, Grice, Dorothy E., Hagstrøm, Julie, Hedderly, Tammy, Heyman, Isobel, Huyser, Chaim, Kim, Young Key, Kim, Young-Shin, Koh, Yun-Joo, Kook, Sodahm, Leventhal, Bennett L., Madruga-Garrido, Marcos, Mir, Pablo, Morer, Astrid, Münchau, Alexander, Plessen, Kerstin J., Roessner, Veit, Shin, Eun-Young, Song, Dong-Ho, Song, Jungeun, Willsey, A. Jeremy, Zinner, Samuel, Fernandez, Thomas, Heiman, Gary, Hoekstra, Pieter, Tischfield, Jay, Woods, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814139/
https://www.ncbi.nlm.nih.gov/pubmed/33462189
http://dx.doi.org/10.1038/s41398-020-01082-z