A Light-Inducible Split-dCas9 System for Inhibiting the Progression of Bladder Cancer Cells by Activating p53 and E-cadherin

Optogenetic systems have been increasingly investigated in the field of biomedicine. Previous studies had found the inhibitory effect of the light-inducible genetic circuits on cancer cell growth. In our study, we applied an AND logic gates to the light-inducible genetic circuits to inhibit the canc...

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Detalles Bibliográficos
Autores principales: Huang, Xinbo, Zhou, Qun, Wang, Mingxia, Cao, Congcong, Ma, Qian, Ye, Jing, Gui, Yaoting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814291/
https://www.ncbi.nlm.nih.gov/pubmed/33469550
http://dx.doi.org/10.3389/fmolb.2020.627848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814291/
https://www.ncbi.nlm.nih.gov/pubmed/33469550
http://dx.doi.org/10.3389/fmolb.2020.627848

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