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Microtubule pivoting enables mitotic spindle assembly in S. cerevisiae

To assemble a bipolar spindle, microtubules emanating from two poles must bundle into an antiparallel midzone, where plus end–directed motors generate outward pushing forces to drive pole separation. Midzone cross-linkers and motors display only modest preferences for antiparallel filaments, and dup...

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Detalles Bibliográficos
Autores principales: Fong, Kimberly K., Davis, Trisha N., Asbury, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814349/
https://www.ncbi.nlm.nih.gov/pubmed/33464308
http://dx.doi.org/10.1083/jcb.202007193