Prevalence and reclassification of BRCA1 and BRCA2 variants in a large, unselected Chinese Han breast cancer cohort

Accurate interpretation of BRCA1/2 variants is critical for risk assessment and precise treatment of breast cancer (BC). Hence, the establishment of an ethnicity-based BRCA1/2 variant database of the Chinese population is of paramount importance. In this study, panel-based sequencing served to detec...

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Detalles Bibliográficos
Autores principales: Liu, Yun, Wang, Honglian, Wang, Xin, Liu, Jiaqi, Li, Junjian, Wang, Xiang, Zhang, Yun, Bai, Zhigang, Zhou, Qinghua, Wu, Ying, Shen, Yi, Weng, Xiaoling, Liu, Fatao, Guo, Jiancheng, Di, Lijun, Gires, Olivier, Zhang, Zhongtao, Chen, Yiding, Wang, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814423/
https://www.ncbi.nlm.nih.gov/pubmed/33461583
http://dx.doi.org/10.1186/s13045-020-01010-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814423/
https://www.ncbi.nlm.nih.gov/pubmed/33461583
http://dx.doi.org/10.1186/s13045-020-01010-0

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