Transplantation of retinal pigment epithelium and photoreceptors generated concomitantly via small molecule-mediated differentiation rescues visual function in rodent models of retinal degeneration

BACKGROUND: Age-related macular degeneration (AMD) is a result of degeneration/damage of the retinal pigment epithelium (RPE) while retinitis pigmentosa (RP), an inherited early-onset disease, results from premature loss of photoreceptors. A promising therapeutic approach for both is the replacement...

Descripción completa

Detalles Bibliográficos
Autores principales: Surendran, Harshini, Nandakumar, Swapna, Reddy K, Vijay Bhaskar, Stoddard, Jonathan, Mohan K, Varsha, Upadhyay, Pramod K., McGill, Trevor J., Pal, Rajarshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814459/
https://www.ncbi.nlm.nih.gov/pubmed/33468244
http://dx.doi.org/10.1186/s13287-021-02134-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814459/
https://www.ncbi.nlm.nih.gov/pubmed/33468244
http://dx.doi.org/10.1186/s13287-021-02134-x

Ejemplares similares