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Jo-1 autoantigen-specific B cells are skewed towards distinct functional B cell subsets in anti-synthetase syndrome patients

BACKGROUND: Anti-Jo-1 autoantibodies which recognize histidyl-tRNA synthetase identify patients with the rare rheumatologic disease, anti-histidyl-tRNA synthetase syndrome (Jo-1 ARS), a phenotypically distinct subset of idiopathic inflammatory myopathies (IIM). Jo-1-binding B cells (JBCs) are implic...

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Detalles Bibliográficos
Autores principales:	Young-Glazer, Jennifer, Cisneros, Alberto, Wilfong, Erin M., Smith, Scott A., Crofford, Leslie J., Bonami, Rachel H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814460/ https://www.ncbi.nlm.nih.gov/pubmed/33468230 http://dx.doi.org/10.1186/s13075-020-02412-8

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