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Transmembrane Prolyl 4-Hydroxylase is a Novel Regulator of Calcium Signaling in Astrocytes

Prolyl 4-hydroxylases (P4Hs) have vital roles in regulating collagen synthesis and hypoxia response. A transmembrane P4H (P4H-TM) is a recently identified member of the family. Biallelic loss of function P4H-TM mutations cause a severe autosomal recessive intellectual disability syndrome in humans,...

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Detalles Bibliográficos
Autores principales: Byts, Nadiya, Sharma, Subodh, Laurila, Jenny, Paudel, Prodeep, Miinalainen, Ilkka, Ronkainen, Veli-Pekka, Hinttala, Reetta, Törnquist, Kid, Koivunen, Peppi, Myllyharju, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814479/
https://www.ncbi.nlm.nih.gov/pubmed/33298456
http://dx.doi.org/10.1523/ENEURO.0253-20.2020