Asparagine Endopeptidase (δ Secretase), an Enzyme Implicated in Alzheimer’s Disease Pathology, Is an Inhibitor of Axon Regeneration in Peripheral Nerves

Asparagine endopeptidase (AEP) is a lysosomal protease implicated in the pathology of Alzheimer’s disease (AD). It is known to cleave the axonal microtubule associated protein, Tau, and amyloid precursor protein (APP), both of which might impede axon regeneration following peripheral nerve injury (P...

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Detalles Bibliográficos
Autores principales: English, Arthur W., Liu, Xia, Mistretta, Olivia C., Ward, Patricia J., Ye, Keqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814480/
https://www.ncbi.nlm.nih.gov/pubmed/33323399
http://dx.doi.org/10.1523/ENEURO.0155-20.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814480/
https://www.ncbi.nlm.nih.gov/pubmed/33323399
http://dx.doi.org/10.1523/ENEURO.0155-20.2020

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