Low levels of PCSK9 are associated with remission in patients with rheumatoid arthritis treated with anti-TNF-α: potential underlying mechanisms

BACKGROUND: Proprotein convertase subtilisin kexin 9 (PCSK9) targets the LDL-receptor (LDLR) which raises LDL-levels. In addition, PCSK9 has proinflammatory immunological effects. Here, we investigate the role of PCSK9 in relation to the inflammatory activity in patients with rheumatoid arthritis (R...

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Detalles Bibliográficos
Autores principales: Frostegård, Johan, Ahmed, Sabbir, Hafström, Ingiäld, Ajeganova, Sofia, Rahman, Mizanur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814540/
https://www.ncbi.nlm.nih.gov/pubmed/33461620
http://dx.doi.org/10.1186/s13075-020-02386-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814540/
https://www.ncbi.nlm.nih.gov/pubmed/33461620
http://dx.doi.org/10.1186/s13075-020-02386-7

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