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Doxorubicin treatment modulates chemoresistance and affects the cell cycle in two canine mammary tumour cell lines
BACKGROUND: Doxorubicin (DOX) is widely used in both human and veterinary oncology although the onset of multidrug resistance (MDR) in neoplastic cells often leads to chemotherapy failure. Better understanding of the cellular mechanisms that circumvent chemotherapy efficacy is paramount. The aim of...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814552/ https://www.ncbi.nlm.nih.gov/pubmed/33461558 http://dx.doi.org/10.1186/s12917-020-02709-5 |