Two cases of carfilzomib‐induced thrombotic microangiopathy successfully treated with Eculizumab in multiple myeloma

BACKGROUND: Treatment with proteasome inhibitors like carfilzomib in patients with multiple myeloma (MM) can induce thrombotic microangiopathy (TMA) characterized by neurological symptoms, acute kidney injury, hemolysis and thrombocytopenia. Successful treatment with the monoclonal antibody eculizum...

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Detalles Bibliográficos
Autores principales: Rassner, Michael, Baur, Rebecca, Wäsch, Ralph, Schiffer, Mario, Schneider, Johanna, Mackensen, Andreas, Engelhardt, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814610/
https://www.ncbi.nlm.nih.gov/pubmed/33461512
http://dx.doi.org/10.1186/s12882-020-02226-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814610/
https://www.ncbi.nlm.nih.gov/pubmed/33461512
http://dx.doi.org/10.1186/s12882-020-02226-5

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