Metabotropic glutamate receptor 5 inhibits α-synuclein-induced microglia inflammation to protect from neurotoxicity in Parkinson’s disease

BACKGROUND: Microglia activation induced by α-synuclein (α-syn) is one of the most important factors in Parkinson’s disease (PD) pathogenesis. However, the molecular mechanisms by which α-syn exerts neuroinflammation and neurotoxicity remain largely elusive. Targeting metabotropic glutamate receptor...

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Detalles Bibliográficos
Autores principales: Zhang, Ya-Nan, Fan, Jing-Kai, Gu, Li, Yang, Hui-Min, Zhan, Shu-Qin, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814625/
https://www.ncbi.nlm.nih.gov/pubmed/33461598
http://dx.doi.org/10.1186/s12974-021-02079-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814625/
https://www.ncbi.nlm.nih.gov/pubmed/33461598
http://dx.doi.org/10.1186/s12974-021-02079-1

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